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AFRO-NETS> RFI: Left Ventricular Failure (2)

  • Subject: AFRO-NETS> RFI: Left Ventricular Failure (2)
  • From: Giuseppe Gramegna <peppegra@tin.it>
  • Date: Wed, 19 Aug 1998 09:59:55 -0400 (EDT)

RFI: Left Ventricular Failure (2)

Chirashree Ray wrote:
> Please may I have some details on the topic below:
> Left ventricular failure - causes and management of acute ventricular
> failure in ICU. Describe stepwise management.

Dear Mr Chirashree,

Left ventricular failure can recognise lots of causes due to some ex-
tremely variable factors: age, sex, cardiac and non-cardiac associates
pathologies (e.g.: congenital, idiopathic, ischaemic, valvular, infec-
tious heart disease, Chagas disease etc.). We actually know two great
pathways for 1) Conventional and 2) Non-conventional treatment of acute
left-heart failure in I.C.U. patients.

The conventional treatment requires a normal I.C.U. environment; after
a general assessment of the patient and the institution of the required
respiratory care, the patient should undergo to a non-invasive (ECG,
blood pressure, temperature etc.) and invasive (BP, CVP, PCWP, etc.)
monitorisation of cardiac and metabolic parameters. Once assessed the
patient and recognised the characters of the failure, the treatment may
consist in the i.v. administration of inotropic drugs, vasodilators,
diuretics and the monitoring of their results on haemodynamic parame-
ters, metabolic acidosis and urinary output.

In the unlikely event of an unsuccessful conventional treatment, we can
adopt, in some cases, two pathways of non-conventional treatment, both
of them need a surgical approach to the patient: 1) Mechanical devices
and 2) Cardiomyoplasty and/or Batista procedure. The mechanical devices
go from I.A.B.P. (Intra-Aortic-Balloon-Pumping, a percutaneous device
containing a balloon inflating in thoracic Aorta during diastolic pe-
riod) to lots of L.V.A.D. (Left-Ventricle-Assist-Device) extra-
corporeal left-circulation in which the blood is drained from the left
auricula and is pumped into systemic circulation through the ascending
or thoracic Aorta or femoral artery) and finally to T.A.H. (Total-
Artificial-Heart), a right and left assist-device without or with an
E.C.M.O. (Extra-Corporeal-Membrane-Oxygenator a true and proper Cardio-
Pulmonary By-Pass).

These devices need a cardio-surgical theatre and a very skilled medical
and nursing staff. Both cardiomyoplasty and Batista operation are a
delicate surgical approach to the left-ventricular failure; they are
generally performable in a secondary, chronical evolution of the dis-
ease, the first consists in the superimposition of a skeletal muscle,
generally the Latissimus Dorsi around the heart and its electrical pac-
ing; the Batista operation is performed to reduce the internal left-
ventricular volume, by cutting a variable quantity of left-ventricular
wall. This is aimed to reduce the wall tension generated by an exces-
sively dilated left ventricle and its consequent sub-endocardic ischae-

I hope that this very general answer and my poor written English will
however increase your cardiac-health programme. I will also be glad to
collaborate having a better knowledge of your patients and of their
most common problems.

Have my regards,
Giuseppe Gramegna

Giuseppe Gramegna Ph.M.D
Cardiac-Surgeon, I.C.U. assistant
Osp. S. Ambrogio Milan
I.C.U. assistant
Osp. S. Raffaele, Rome, Italy

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